#include "RooGlobalFunc.h" #include "RooRealVar.h" #include "RooProdPdf.h" #include "RooWorkspace.h" #include "RooDataSet.h" #include "TCanvas.h" #include "TStopwatch.h" #include "TH1.h" #include "RooPlot.h" #include "RooMsgService.h" #include "RooStats/NumberCountingUtils.h" #include "RooStats/HybridCalculator.h" #include "RooStats/ToyMCSampler.h" #include "RooStats/HypoTestPlot.h" #include "RooStats/ProfileLikelihoodTestStat.h" #include "RooStats/SimpleLikelihoodRatioTestStat.h" #include "RooStats/RatioOfProfiledLikelihoodsTestStat.h" #include "RooStats/MaxLikelihoodEstimateTestStat.h" using namespace RooFit; using namespace RooStats; // ---------------------------------- // A New Test Statistic Class for this example. // It simply returns the sum of the values in a particular // column of a dataset. // You can ignore this class and focus on the macro below class BinCountTestStat : public TestStatistic { public: BinCountTestStat(void) : fColumnName("tmp") {} BinCountTestStat(string columnName) : fColumnName(columnName) {} virtual Double_t Evaluate(RooAbsData &data, RooArgSet & /*nullPOI*/) { // This is the main method in the interface Double_t value = 0.0; for (int i = 0; i < data.numEntries(); i++) { value += data.get(i)->getRealValue(fColumnName.c_str()); } return value; } virtual const TString GetVarName() const { return fColumnName; } private: string fColumnName; protected: ClassDef(BinCountTestStat, 1) }; // ---------------------------------- // The Actual Tutorial Macro void HybridInstructional(int ntoys = 6000) { double nToysRatio = 20; // ratio Ntoys Null/ntoys ALT // This tutorial has 6 parts // Table of Contents // Setup // 1. Make the model for the 'prototype problem' // Special cases // 2. Use RooFit's direct integration to get p-value & significance // 3. Use RooStats analytic solution for this problem // RooStats HybridCalculator -- can be generalized // 4. RooStats ToyMC version of 2. & 3. // 5. RooStats ToyMC with an equivalent test statistic // 6. RooStats ToyMC with simultaneous control & main measurement TStopwatch t; t.Start(); TCanvas *c = new TCanvas; c->Divide(2, 2); // ---------------------------------------------------- // P A R T 1 : D I R E C T I N T E G R A T I O N // ==================================================== // Make model for prototype on/off problem // $Pois(x | s+b) * Pois(y | tau b )$ // for Z_Gamma, use uniform prior on b. RooWorkspace *w = new RooWorkspace("w"); w->factory("Poisson::px(x[150,0,500],sum::splusb(s[0,0,100],b[100,0.1,300]))"); w->factory("Poisson::py(y[100,0.1,500],prod::taub(tau[1.],b))"); w->factory("PROD::model(px,py)"); w->factory("Uniform::prior_b(b)"); // We will control the output level in a few places to avoid // verbose progress messages. We start by keeping track // of the current threshold on messages. RooFit::MsgLevel msglevel = RooMsgService::instance().globalKillBelow(); // ---------------------------------------------------- // P A R T 2 : D I R E C T I N T E G R A T I O N // ==================================================== // This is not the 'RooStats' way, but in this case the distribution // of the test statistic is simply x and can be calculated directly // from the PDF using RooFit's built-in integration. // Note, this does not generalize to situations in which the test statistic // depends on many events (rows in a dataset). // construct the Bayesian-averaged model (eg. a projection pdf) // $p'(x|s) = \int db p(x|s+b) * [ p(y|b) * prior(b) ]$ w->factory("PROJ::averagedModel(PROD::foo(px|b,py,prior_b),b)"); RooMsgService::instance().setGlobalKillBelow(RooFit::ERROR); // lower message level // plot it, red is averaged model, green is b known exactly, blue is s+b av model RooPlot *frame = w->var("x")->frame(Range(50, 230)); w->pdf("averagedModel")->plotOn(frame, LineColor(kRed)); w->pdf("px")->plotOn(frame, LineColor(kGreen)); w->var("s")->setVal(50.); w->pdf("averagedModel")->plotOn(frame, LineColor(kBlue)); c->cd(1); frame->Draw(); w->var("s")->setVal(0.); // compare analytic calculation of Z_Bi // with the numerical RooFit implementation of Z_Gamma // for an example with x = 150, y = 100 // numeric RooFit Z_Gamma w->var("y")->setVal(100); w->var("x")->setVal(150); std::unique_ptr cdf{w->pdf("averagedModel")->createCdf(*w->var("x"))}; cdf->getVal(); // get ugly print messages out of the way cout << "-----------------------------------------" << endl; cout << "Part 2" << endl; cout << "Hybrid p-value from direct integration = " << 1 - cdf->getVal() << endl; cout << "Z_Gamma Significance = " << PValueToSignificance(1 - cdf->getVal()) << endl; RooMsgService::instance().setGlobalKillBelow(msglevel); // set it back // --------------------------------------------- // P A R T 3 : A N A L Y T I C R E S U L T // ============================================= // In this special case, the integrals are known analytically // and they are implemented in RooStats::NumberCountingUtils // analytic Z_Bi double p_Bi = NumberCountingUtils::BinomialWithTauObsP(150, 100, 1); double Z_Bi = NumberCountingUtils::BinomialWithTauObsZ(150, 100, 1); cout << "-----------------------------------------" << endl; cout << "Part 3" << endl; std::cout << "Z_Bi p-value (analytic): " << p_Bi << std::endl; std::cout << "Z_Bi significance (analytic): " << Z_Bi << std::endl; t.Stop(); t.Print(); t.Reset(); t.Start(); // ------------------------------------------------------------- // P A R T 4 : U S I N G H Y B R I D C A L C U L A T O R // ============================================================= // Now we demonstrate the RooStats HybridCalculator. // // Like all RooStats calculators it needs the data and a ModelConfig // for the relevant hypotheses. Since we are doing hypothesis testing // we need a ModelConfig for the null (background only) and the alternate // (signal+background) hypotheses. We also need to specify the PDF, // the parameters of interest, and the observables. Furthermore, since // the parameter of interest is floating, we need to specify which values // of the parameter corresponds to the null and alternate (eg. s=0 and s=50) // // define some sets of variables obs={x} and poi={s} // note here, x is the only observable in the main measurement // and y is treated as a separate measurement, which is used // to produce the prior that will be used in this calculation // to randomize the nuisance parameters. w->defineSet("obs", "x"); w->defineSet("poi", "s"); // create a toy dataset with the x=150 RooDataSet *data = new RooDataSet("d", "d", *w->set("obs")); data->add(*w->set("obs")); // Part 3a : Setup ModelConfigs // ------------------------------------------------------- // create the null (background-only) ModelConfig with s=0 ModelConfig b_model("B_model", w); b_model.SetPdf(*w->pdf("px")); b_model.SetObservables(*w->set("obs")); b_model.SetParametersOfInterest(*w->set("poi")); w->var("s")->setVal(0.0); // important! b_model.SetSnapshot(*w->set("poi")); // create the alternate (signal+background) ModelConfig with s=50 ModelConfig sb_model("S+B_model", w); sb_model.SetPdf(*w->pdf("px")); sb_model.SetObservables(*w->set("obs")); sb_model.SetParametersOfInterest(*w->set("poi")); w->var("s")->setVal(50.0); // important! sb_model.SetSnapshot(*w->set("poi")); // Part 3b : Choose Test Statistic // ---------------------------------- // To make an equivalent calculation we need to use x as the test // statistic. This is not a built-in test statistic in RooStats // so we define it above. The new class inherits from the // RooStats::TestStatistic interface, and simply returns the value // of x in the dataset. BinCountTestStat binCount("x"); // Part 3c : Define Prior used to randomize nuisance parameters // ------------------------------------------------------------- // // The prior used for the hybrid calculator is the posterior // from the auxiliary measurement y. The model for the aux. // measurement is Pois(y|tau*b), thus the likelihood function // is proportional to (has the form of) a Gamma distribution. // if the 'original prior' $\eta(b)$ is uniform, then from // Bayes's theorem we have the posterior: // $\pi(b) = Pois(y|tau*b) * \eta(b)$ // If $\eta(b)$ is flat, then we arrive at a Gamma distribution. // Since RooFit will normalize the PDF we can actually supply // $py=Pois(y,tau*b)$ that will be equivalent to multiplying by a uniform. // // Alternatively, we could explicitly use a gamma distribution: // `w->factory("Gamma::gamma(b,sum::temp(y,1),1,0)");` // // or we can use some other ad hoc prior that do not naturally // follow from the known form of the auxiliary measurement. // The common choice is the equivalent Gaussian: w->factory("Gaussian::gauss_prior(b,y, expr::sqrty('sqrt(y)',y))"); // this corresponds to the "Z_N" calculation. // // or one could use the analogous log-normal prior w->factory("Lognormal::lognorm_prior(b,y, expr::kappa('1+1./sqrt(y)',y))"); // // Ideally, the HybridCalculator would be able to inspect the full // model $Pois(x | s+b) * Pois(y | tau b )$ and be given the original // prior $\eta(b)$ to form $\pi(b) = Pois(y|tau*b) * \eta(b)$. // This is not yet implemented because in the general case // it is not easy to identify the terms in the PDF that correspond // to the auxiliary measurement. So for now, it must be set // explicitly with: // - ForcePriorNuisanceNull() // - ForcePriorNuisanceAlt() // the name "ForcePriorNuisance" was chosen because we anticipate // this to be auto-detected, but will leave the option open // to force to a different prior for the nuisance parameters. // Part 3d : Construct and configure the HybridCalculator // ------------------------------------------------------- HybridCalculator hc1(*data, sb_model, b_model); ToyMCSampler *toymcs1 = (ToyMCSampler *)hc1.GetTestStatSampler(); toymcs1->SetNEventsPerToy(1); // because the model is in number counting form toymcs1->SetTestStatistic(&binCount); // set the test statistic hc1.SetToys(ntoys, ntoys / nToysRatio); hc1.ForcePriorNuisanceAlt(*w->pdf("py")); hc1.ForcePriorNuisanceNull(*w->pdf("py")); // if you wanted to use the ad hoc Gaussian prior instead // ~~~ // hc1.ForcePriorNuisanceAlt(*w->pdf("gauss_prior")); // hc1.ForcePriorNuisanceNull(*w->pdf("gauss_prior")); // ~~~ // if you wanted to use the ad hoc log-normal prior instead // ~~~ // hc1.ForcePriorNuisanceAlt(*w->pdf("lognorm_prior")); // hc1.ForcePriorNuisanceNull(*w->pdf("lognorm_prior")); // ~~~ // these lines save current msg level and then kill any messages below ERROR RooMsgService::instance().setGlobalKillBelow(RooFit::ERROR); // Get the result HypoTestResult *r1 = hc1.GetHypoTest(); RooMsgService::instance().setGlobalKillBelow(msglevel); // set it back cout << "-----------------------------------------" << endl; cout << "Part 4" << endl; r1->Print(); t.Stop(); t.Print(); t.Reset(); t.Start(); c->cd(2); HypoTestPlot *p1 = new HypoTestPlot(*r1, 30); // 30 bins, TS is discrete p1->Draw(); // ------------------------------------------------------------------------- // # P A R T 5 : U S I N G H Y B R I D C A L C U L A T O R // # W I T H A N A L T E R N A T I V E T E S T S T A T I S T I C // // A likelihood ratio test statistics should be 1-to-1 with the count x // when the value of b is fixed in the likelihood. This is implemented // by the SimpleLikelihoodRatioTestStat SimpleLikelihoodRatioTestStat slrts(*b_model.GetPdf(), *sb_model.GetPdf()); slrts.SetNullParameters(*b_model.GetSnapshot()); slrts.SetAltParameters(*sb_model.GetSnapshot()); // HYBRID CALCULATOR HybridCalculator hc2(*data, sb_model, b_model); ToyMCSampler *toymcs2 = (ToyMCSampler *)hc2.GetTestStatSampler(); toymcs2->SetNEventsPerToy(1); toymcs2->SetTestStatistic(&slrts); hc2.SetToys(ntoys, ntoys / nToysRatio); hc2.ForcePriorNuisanceAlt(*w->pdf("py")); hc2.ForcePriorNuisanceNull(*w->pdf("py")); // if you wanted to use the ad hoc Gaussian prior instead // ~~~ // hc2.ForcePriorNuisanceAlt(*w->pdf("gauss_prior")); // hc2.ForcePriorNuisanceNull(*w->pdf("gauss_prior")); // ~~~ // if you wanted to use the ad hoc log-normal prior instead // ~~~ // hc2.ForcePriorNuisanceAlt(*w->pdf("lognorm_prior")); // hc2.ForcePriorNuisanceNull(*w->pdf("lognorm_prior")); // ~~~ // these lines save current msg level and then kill any messages below ERROR RooMsgService::instance().setGlobalKillBelow(RooFit::ERROR); // Get the result HypoTestResult *r2 = hc2.GetHypoTest(); cout << "-----------------------------------------" << endl; cout << "Part 5" << endl; r2->Print(); t.Stop(); t.Print(); t.Reset(); t.Start(); RooMsgService::instance().setGlobalKillBelow(msglevel); c->cd(3); HypoTestPlot *p2 = new HypoTestPlot(*r2, 30); // 30 bins p2->Draw(); // ----------------------------------------------------------------------------- // # P A R T 6 : U S I N G H Y B R I D C A L C U L A T O R W I T H A N A L T E R N A T I V E T E S T // # S T A T I S T I C A N D S I M U L T A N E O U S M O D E L // // If one wants to use a test statistic in which the nuisance parameters // are profiled (in one way or another), then the PDF must constrain b. // Otherwise any observation x can always be explained with s=0 and b=x/tau. // // In this case, one is really thinking about the problem in a // different way. They are considering x,y simultaneously. // and the PDF should be $Pois(x | s+b) * Pois(y | tau b )$ // and the set 'obs' should be {x,y}. w->defineSet("obsXY", "x,y"); // create a toy dataset with the x=150, y=100 w->var("x")->setVal(150.); w->var("y")->setVal(100.); RooDataSet *dataXY = new RooDataSet("dXY", "dXY", *w->set("obsXY")); dataXY->add(*w->set("obsXY")); // now we need new model configs, with PDF="model" ModelConfig b_modelXY("B_modelXY", w); b_modelXY.SetPdf(*w->pdf("model")); // IMPORTANT b_modelXY.SetObservables(*w->set("obsXY")); b_modelXY.SetParametersOfInterest(*w->set("poi")); w->var("s")->setVal(0.0); // IMPORTANT b_modelXY.SetSnapshot(*w->set("poi")); // create the alternate (signal+background) ModelConfig with s=50 ModelConfig sb_modelXY("S+B_modelXY", w); sb_modelXY.SetPdf(*w->pdf("model")); // IMPORTANT sb_modelXY.SetObservables(*w->set("obsXY")); sb_modelXY.SetParametersOfInterest(*w->set("poi")); w->var("s")->setVal(50.0); // IMPORTANT sb_modelXY.SetSnapshot(*w->set("poi")); // Test statistics like the profile likelihood ratio // (or the ratio of profiled likelihoods (Tevatron) or the MLE for s) // will now work, since the nuisance parameter b is constrained by y. // ratio of alt and null likelihoods with background yield profiled. // // NOTE: These are slower because they have to run fits for each toy // Tevatron-style Ratio of profiled likelihoods // $Q_Tev = -log L(s=0,\hat\hat{b})/L(s=50,\hat\hat{b})$ RatioOfProfiledLikelihoodsTestStat ropl(*b_modelXY.GetPdf(), *sb_modelXY.GetPdf(), sb_modelXY.GetSnapshot()); ropl.SetSubtractMLE(false); // profile likelihood where alternate is best fit value of signal yield // $\lambda(0) = -log L(s=0,\hat\hat{b})/L(\hat{s},\hat{b})$ ProfileLikelihoodTestStat profll(*b_modelXY.GetPdf()); // just use the maximum likelihood estimate of signal yield // $MLE = \hat{s}$ MaxLikelihoodEstimateTestStat mlets(*sb_modelXY.GetPdf(), *w->var("s")); // However, it is less clear how to justify the prior used in randomizing // the nuisance parameters (since that is a property of the ensemble, // and y is a property of each toy pseudo experiment. In that case, // one probably wants to consider a different y0 which will be held // constant and the prior $\pi(b) = Pois(y0 | tau b) * \eta(b)$. w->factory("y0[100]"); w->factory("Gamma::gamma_y0(b,sum::temp0(y0,1),1,0)"); w->factory("Gaussian::gauss_prior_y0(b,y0, expr::sqrty0('sqrt(y0)',y0))"); // HYBRID CALCULATOR HybridCalculator hc3(*dataXY, sb_modelXY, b_modelXY); ToyMCSampler *toymcs3 = (ToyMCSampler *)hc3.GetTestStatSampler(); toymcs3->SetNEventsPerToy(1); toymcs3->SetTestStatistic(&slrts); hc3.SetToys(ntoys, ntoys / nToysRatio); hc3.ForcePriorNuisanceAlt(*w->pdf("gamma_y0")); hc3.ForcePriorNuisanceNull(*w->pdf("gamma_y0")); // if you wanted to use the ad hoc Gaussian prior instead // ~~~{.cpp} // hc3.ForcePriorNuisanceAlt(*w->pdf("gauss_prior_y0")); // hc3.ForcePriorNuisanceNull(*w->pdf("gauss_prior_y0")); // ~~~ // choose fit-based test statistic toymcs3->SetTestStatistic(&profll); // toymcs3->SetTestStatistic(&ropl); // toymcs3->SetTestStatistic(&mlets); // these lines save current msg level and then kill any messages below ERROR RooMsgService::instance().setGlobalKillBelow(RooFit::ERROR); // Get the result HypoTestResult *r3 = hc3.GetHypoTest(); cout << "-----------------------------------------" << endl; cout << "Part 6" << endl; r3->Print(); t.Stop(); t.Print(); t.Reset(); t.Start(); RooMsgService::instance().setGlobalKillBelow(msglevel); c->cd(4); c->GetPad(4)->SetLogy(); HypoTestPlot *p3 = new HypoTestPlot(*r3, 50); // 50 bins p3->Draw(); c->SaveAs("zbi.pdf"); // ----------------------------------------- // OUTPUT (2.66 GHz Intel Core i7) // ========================================= // ----------------------------------------- // Part 2 // Hybrid p-value from direct integration = 0.00094165 // Z_Gamma Significance = 3.10804 // ----------------------------------------- // // Part 3 // Z_Bi p-value (analytic): 0.00094165 // Z_Bi significance (analytic): 3.10804 // Real time 0:00:00, CP time 0.610 // ----------------------------------------- // Part 4 // Results HybridCalculator_result: // - Null p-value = 0.00115 +/- 0.000228984 // - Significance = 3.04848 sigma // - Number of S+B toys: 1000 // - Number of B toys: 20000 // - Test statistic evaluated on data: 150 // - CL_b: 0.99885 +/- 0.000239654 // - CL_s+b: 0.476 +/- 0.0157932 // - CL_s: 0.476548 +/- 0.0158118 // Real time 0:00:07, CP time 7.620 // ----------------------------------------- // Part 5 // Results HybridCalculator_result: // - Null p-value = 0.0009 +/- 0.000206057 // - Significance = 3.12139 sigma // - Number of S+B toys: 1000 // - Number of B toys: 20000 // - Test statistic evaluated on data: 10.8198 // - CL_b: 0.9991 +/- 0.000212037 // - CL_s+b: 0.465 +/- 0.0157726 // - CL_s: 0.465419 +/- 0.0157871 // Real time 0:00:34, CP time 34.360 // ----------------------------------------- // Part 6 // Results HybridCalculator_result: // - Null p-value = 0.000666667 +/- 0.000149021 // - Significance = 3.20871 sigma // - Number of S+B toys: 1000 // - Number of B toys: 30000 // - Test statistic evaluated on data: 5.03388 // - CL_b: 0.999333 +/- 0.000149021 // - CL_s+b: 0.511 +/- 0.0158076 // - CL_s: 0.511341 +/- 0.0158183 // Real time 0:05:06, CP time 306.330 // ---------------------------------- // Comparison // ---------------------------------- // LEPStatToolsForLHC // https://plone4.fnal.gov:4430/P0/phystat/packages/0703002 // Uses Gaussian prior // CL_b = 6.218476e-04, Significance = 3.228665 sigma // // ---------------------------------- // Comparison // ---------------------------------- // Asymptotic // From the value of the profile likelihood ratio (5.0338) // The significance can be estimated using Wilks's theorem // significance = sqrt(2*profileLR) = 3.1729 sigma }